A Patient With Common Variable Immunodeficiency and Pericardial Effusion

Severe bronchiectasis in a patient with common variable immunodeficiency.

BACKGROUND Bronchiectasis are common in Common Variable Immunodeficiency. These patients are prone to infection, leading to progressive lung destruction and accelerated FEV1 decline. CLINICAL CASE 40 year-old man, with recurrent respiratory infections, autoimmunity and diarrhea since age 7. At 17 CVID was diagnosed and IVIgG was started. During the following years, respiratory symptoms progre...

Cutaneous granulomas in a patient with common variable immunodeficiency.

Sir, Common variable immunode¢ciency (CVID), one of the most frequent of the primary speci¢c immunode¢ciencies, is a heterogeneous group of syndromes characterized by a de¢ciency in antibody synthesis associated with panhypogammaglobulinaemia and recurrent bacterial infections (1). The occurrence of non-caseating granulomas in di¡erent organs, including the skin, has been described previously. ...

Nocardiosis in a patient with common variable immunodeficiency.

We report a case of nocardiosis in a 42, years male with common variable immunodeficiency syndrome (CVID). He presented with arthritis, subcutaneous abscess and pleural effusion. Diagnosis of CVID was made during this presentation. Serum IgG, IgA and IgM levels were markedly decreased. Nocardia asteroides was cultured from pleural fluid. He was successfully treated with intravenous immunoglobul...

Secondary Amenorrhea in a Patient with Common Variable Immunodeficiency

Pyoderma gangrenosum in a patient with common variable primary immunodeficiency

Pyoderma gangrenosum is a rare inflammatory skin condition that is associated with systemic inflammatory diseases. It is characterised by the presence of well-secluded, painful ulcerations, often located on the lower limbs. Similarly as in the case of acne inversa, patients' markers of the inflammatory process are elevated; including OB, C-reactive protein and leukocytosis. The aetiology takes ...